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Targeted Organ or Multiple Organ Delivery of mRNA with Ionizable Amphiphilic Janus Dendrimers

A library of easily synthesized ionizable amphiphilic Janus dendrimer (IAJD) compounds that deliver mRNA either to targeted organs or multiple organs, depending on the IAJD design.

Published: 7/23/2024
Inventor(s):
Virgil Percec, Drew Weissman, Juncheng (Luke) Lu, Elena Atochina-Vasserman, Devendra Maurya, Dipankar Sahoo
Keywords(s):
Drug Delivery, Platform Technology
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Vaccines