Search Results - technology+classifications+%3e+vaccines

Modified Antimicrobial Peptides For Enhanced Antibiotic Properties

Modified antimicrobial peptides with protein sequences for augmenting antimicrobial and antibiofilm properties.

Published: 3/13/2024

Direct and Effective Method To Reverse The Effects of Fragile X Syndrome

A method of treating Fragile X syndrome by correcting the abnormal DNA clusters causing the characteristic symptoms.

Published: 3/8/2024

Inventor(s):

Jennifer Phillips-Cremins, Linda Zhou, Chunmin GE

Keywords(s):

Bioengineering, Gene Therapy, Genetic Disorders, Neurodegenerative Diseases, Neurology

Category(s):

Technology Classifications > Therapeutics, Technology Classifications > Vaccines

RGD Peptide-Based Lipids For Targeted mRNA Delivery and Gene Editing Applications

A combinatorial library of RGD peptide (arginine-glycine-aspartic acid)-based lipids designed to formulate lipid nanoparticles for targeted mRNA delivery to the liver and the spleen.

Published: 2/7/2024

Inventor(s):

Michael Mitchell, Lulu Xue, Jingya Qin

Keywords(s):

Bioengineering, Drug Delivery, Gene Editing, Oncology, Platform Technology

Category(s):

Technology Classifications > Therapeutics, Technology Classifications > Vaccines

Modified Lipid Nanoparticle Formulations with Improved Therapeutic Delivery to the Bone Microenvironment In-vivo

A library of bi-phosphonate ionizable lipids and LNP formulations to facilitate mRNA delivery to the bone microenvironment.

Published: 2/7/2024

Inventor(s):

Michael Mitchell, Lulu Xue

Keywords(s):

Drug Delivery, Drug Target, Nanotechnology, Orthopedics, Platform Technology, Regenerative Medicine

Category(s):

Technology Classifications > Vaccines, Technology Classifications > Therapeutics, Technology Classifications > Research Tools & Reagents

Ligand-Tethered Lipid Nanoparticles for Targeted RNA Delivery to Treat Liver Fibrosis

A new class of anisimide-functionalized lipids that enables targeted delivery of lipid nanoparticles (LNPs) to activated fibroblasts in the liver.

Published: 2/7/2024

Inventor(s):

Michael Mitchell, Xuexiang Han

Keywords(s):

Bioengineering, Drug Delivery, Gene Editing, Gene Therapy, Genetic Disorders, Immunology, Immunoncology, Platform Technology, Regenerative Medicine

Category(s):

Technology Classifications > Therapeutics, Technology Classifications > Vaccines

Peptide Inhibitor to Treat Cancers and COVID-19 While Decreasing Off-Target Side Effects

Thioamide-stabilized peptide specifically inhibiting cathepsin L to block SARS-CoV-2 entry and cancer cell migration

Published: 1/5/2024

Inventor(s):

E. James Petersson, Hoang Anh T. Phan

Keywords(s):

Immunology, Immunoncology, Oncology

Category(s):

Technology Classifications > Therapeutics, Technology Classifications > Vaccines

Engineered Wasp Venom for Safe and Effective Antibiotics

A method for manipulating wasp venom peptide to maintain antimicrobial properties while reducing human toxicity.

Published: 10/16/2023

Inventor(s):

Marcelo Der Torossian Torres, Cesar de la Fuente-Nunez

Keywords(s):

Bioengineering, Infectious Disease, Inflammation, Protein/Peptide (Non-Antibody)

Category(s):

Technology Classifications > Therapeutics, Technology Classifications > Vaccines

CD137 enrichment of tumor-specific tumor-infiltrating lymphocytes (TILs)

A platform to isolate and expand CD137-positive (CD137^pos) tumor-infiltrating lymphocytes (TILs) to use in adoptive immunotherapy and translational studies.