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Cationic steroids as antimicrobial agents
Antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate Overview Technology: The emergence of antibiotic-resistant bacteria is a rising health crisis that requires the development of new antibacterial agents. Cationic steroids disrupt bacterial membranes via physical and chemical mechanisms that...
Published: 3/17/2020   |   Inventor(s): Paul Janmey, Scott Diamond
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Research Tools & Reagents, Therapeutics & Vaccines
One-step synthesis of cationic steroids for gene delivery, anti-inflammatory activity, and antimicrobial activity.
Reagents for improved DNA lipofection, depot anti-inflammation, and/or topical antimicrobial therapy Technology Overview: Researchers in the Diamond Lab have developed a versatile new class of pharmacologically-active molecules with multiple applications. These molecules deliver plasmids (pDNA), adenovirus (AdV), and adeno-associated virus (AAV)...
Published: 11/27/2018   |   Inventor(s): Scott Diamond
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Research Tools & Reagents, Therapeutics & Vaccines