An optofluidic platform to detect extracellular vesicles (EVs) at the single-particle level by parallelizing droplet generation and analysis of EVs.
Synergistic combination of mechanoporation and lipid nanoparticle (LNP) based transfection for an efficient, non-viral method of gene transfer to generate CAR-T cell therapies.
A microfluidic device allowing spatiotemporal manipulation of droplets that can be applied to high-resolution analytical techniques.
A photoresponsive polymer layer that can be integrated into microfluidic devices for selective release of unique droplets
Method to transfer wettability properties of a mold to microfluidic devices, defining hydrophobic/hydrophilic regions through variable perfluoropolyether concentration.
Employment of omniphobic, thin-layer perfluorocarbon (TLP) coating to prevent fouling and clogging in microfluidic mixing devices during mRNA LNP formulations.
An ultrasensitive diagnostic tool that isolates single extracellular vesicles (EVs) and measures their contents to single molecule resolution.
A polymer brush coating on a substrate made through block copolymer coating and exfoliation for pH-mediated nanoparticle sorting, transport, and diffusion.
Device that simultaneously injects fluid into and removes fluid from droplets in flow.
A scalable, parallelized, multi-channel microfluidic device for generating lipid nanoparticles.