Innovation at Penn
Browse Penn-owned technologies available for licensing.
Search Results - jennifer phillips-cremins
Light-inducible CRISPR-Cas9 dimerization system for engineering 3D chromatin topology
An optogenetic CRISPR-Cas9 system for inducing reversible, three-dimensional chromatin loops to regulate target gene expression. Technology Overview: Mammalian genomes are folded through tens of thousands of chromatin interactions. However, these interactions and the topology of the genome are still poorly understood, especially with respect to...
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