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Ionizable Lipid Nanoparticles with Low Immunogenicity Which Enable Repeated Administrations of mRNAs Encoding Gene Editors, Tumor Neoantigens, and Vaccine Payloads.

Using Mannich reaction-based combinatorial libraries to identify ionizable lipids for low-immunogenic and high-efficiency mRNA delivery.

Published: 10/1/2024
Inventor(s):
Michael Mitchell, Ningqiang Gong
Keywords(s):
Bioengineering, Drug Delivery
Category(s):
Technology Classifications > Therapeutics