Search Results - lulu+xue

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Lipid Nanoparticles That Specifically Target The Lungs

Lung-targeting lipid nanoparticles allowing organ specific mRNA delivery for gene therapy applications.

Published: 10/17/2024
Inventor(s):
Michael Mitchell, Lulu Xue
Keywords(s):
Bioengineering, COVID-19, Gene Therapy, Infectious Disease, Pulmonary
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics, Technology Classifications > Vaccines

RGD Peptide-Based Lipids For Targeted mRNA Delivery and Gene Editing Applications

A combinatorial library of RGD peptide (arginine-glycine-aspartic acid)-based lipids designed to formulate lipid nanoparticles for targeted mRNA delivery to the liver and the spleen.

Published: 2/7/2024
Inventor(s):
Michael Mitchell, Lulu Xue, Jingya Qin
Keywords(s):
Bioengineering, Drug Delivery, Gene Editing, Oncology, Platform Technology
Category(s):
Technology Classifications > Therapeutics, Technology Classifications > Vaccines

Modified Lipid Nanoparticle Formulations with Improved Therapeutic Delivery to the Bone Microenvironment In-vivo

A library of bi-phosphonate ionizable lipids and LNP formulations to facilitate mRNA delivery to the bone microenvironment. 

Published: 2/7/2024
Inventor(s):
Michael Mitchell, Lulu Xue
Keywords(s):
Drug Delivery, Drug Target, Nanotechnology, Orthopedics, Platform Technology, Regenerative Medicine
Category(s):
Technology Classifications > Vaccines, Technology Classifications > Therapeutics, Technology Classifications > Research Tools & Reagents