Search Results - lulu+xue

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Biocompatible And Low-Toxicity Lipid Nanoparticles (LNPs) For Selectively Delivering mRNA To The Bone Microenvironment

Ionizable LNPs with a rigid backbone of piperazine (PIP) linked to bisphosphonates (BPs) for the targeted delivery of mRNA to the bone.

Published: 10/3/2025

Inventor(s):

Michael Mitchell, Kyle Vining, Lulu Xue, Il-Chul Yoon

Keywords(s):

Aging, Bioengineering, Drug Delivery, Gene Therapy, Orthopedics, Platform Technology, Women's Health

Category(s):

Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics

Lipid Nanoparticles That Specifically Target The Lungs

Lung-targeting lipid nanoparticles allowing organ specific mRNA delivery for gene therapy applications.

Published: 11/26/2025

Inventor(s):

Michael Mitchell, Lulu Xue

Keywords(s):

Bioengineering, COVID-19, Gene Therapy, Infectious Disease, Pulmonary

Category(s):

Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics, Technology Classifications > Vaccines

Modified Lipid Nanoparticle Formulations with Improved Therapeutic Delivery to the Bone Microenvironment In-vivo

A library of bi-phosphonate ionizable lipids and LNP formulations to facilitate mRNA delivery to the bone microenvironment.

Published: 11/26/2025

Inventor(s):

Michael Mitchell, Lulu Xue

Keywords(s):

Drug Delivery, Drug Target, Nanotechnology, Orthopedics, Platform Technology, Regenerative Medicine

Category(s):

Technology Classifications > Vaccines, Technology Classifications > Therapeutics, Technology Classifications > Research Tools & Reagents